Research on the evolution of the Chinese urban biomedicine innovation network pattern: An analysis using multispatial scales.

This paper addresses the spatial pattern of urban biomedicine innovation networks by separately using four scales, i.e., the national scale, interregional scale, urban agglomeration scale, and provincial scale, on the basis of Chinese biomedicine patent data from the incoPat global patent database (GPD) (2001-2020) and using the method of social network analysis (SNA). Through the research, it is found that (1) on the national scale, the Chinese biomedicine innovation network becomes denser from west to the east as its complexity continuously increases. Its spatial structure takes the form of a radial network pattern with Beijing and Shanghai as its centers. The COVID-19 pandemic has not had an obvious negative impact on this network at present. (2) On the interregional scale, the strength of interregional network ties is greater than that of intraregional network ties. The eastern, central and western biomedicine innovation networks appear to be heterogeneous networks with regional central cities as the cores. (3) At the urban agglomeration scale, the strength of intraurban-agglomeration network ties is greater than that of interurban-agglomeration network ties. The three major urban agglomerations have formed radial spatial patterns with central cities as the hubs. (4) At the provincial scale, the intraprovincial networks have poor connectivity and low internal ties strength, which manifest as core-periphery structures with the provincial capitals as centers. Our research conclusion helps to clarify the current accumulation of technology and offer guidance for the development of China's biomedicine industry.

Structural characteristics of China's COVID-19 patent cooperation network at the province, city, and patent applicant levels.

The Chinese Plan has provided an important model for the global fight against COVID-19 since its outbreak. The present study describes the structural characteristics of China's COVID-19 patent cooperation network at the province, city, and applicant levels by using social network analysis based on data from the Incopat global patent database since 2020, which helps to clarify the current technology accumulation in this field in China, and provide patent information support for the scientific efforts to fight against COVID-19. The findings are as follows: First, the inter-regional cooperation level in China's COVID-19 patent cooperation network shows a decreasing trend from eastern to central to western regions. At the inter-applicant cooperation level, kinship-based cooperation is the strongest, business-based cooperation has the widest scope, while proximity-based cooperation exists throughout these two main models of cooperation. Second, coastal provinces and cities occupy a core position in the network, and play an important role in utilizing structural holes and bridging. Patent applicants with high centrality are mostly firms. Research institutes and universities mainly play the role of bridges. Third and lastly, there is no large number of cliques at the province and city levels. However, there is a tendency for cliques to develop at the applicant level. Hence, actions are needed to prevent the development of information barriers.